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Table 3 Pregnancy outcomes stratified by thyroid function and Autoantibody Status

From: Impact of maternal thyroid dysfunction on fetal and maternal outcomes in pregnancy: a prospective cohort study

Outcome

Euthyroid (n = 500)

Hypothyroid (n = 250)

Hyperthyroid (n = 150)

 

Ab+ (n = 250)

Ab- (n = 250)

Ab+ (n = 125)

Ab- (n = 125)

Ab+ (n = 75)

Ab- (n = 75)

Fetal Outcomes

      

Preterm birth

21 (8.4%)

15 (6.0%)

18 (14.4%)

14 (11.2%)

8 (10.7%)

7 (9.3%)

Low birth weight

18 (7.2%)

13 (5.2%)

16 (12.8%)

12 (9.6%)

7 (9.3%)

5 (6.7%)

NICU admission

23 (9.2%)

17 (6.8%)

20 (16.0%)

16 (12.8%)

9 (12.0%)

7 (9.3%)

Low APGAR score

17 (6.8%)

12 (4.8%)

14 (11.2%)

11 (8.8%)

7 (9.3%)

5 (6.7%)

Maternal Outcomes

      

Preeclampsia

19 (7.6%)

13 (5.2%)

25 (20.0%)

21 (16.8%)

7 (9.3%)

5 (6.7%)

Postpartum hemorrhage

23 (9.2%)

18 (7.2%)

18 (14.4%)

15 (12.0%)

9 (12.0%)

7 (9.3%)

Gestational hypertension

22 (8.8%)

16 (6.4%)

17 (13.6%)

14 (11.2%)

8 (10.7%)

6 (8.0%)

Postpartum thyroiditis

13 (5.2%)

5 (2.0%)

11 (8.8%)

4 (3.2%)

7 (9.3%)

3 (4.0%)

  1. Ab+: Autoantibody positive (TPOAb > 12 IU/mL or TgAb > 15 IU/mL) Ab-: Autoantibody negative