Table 1 The summary of the studies
From: Specular microscopy findings in diabetic patients: a systematic review and meta-analysis
Author | Year | Sample size | Groups | Endothelial Cell Density (cells/m2) | Average cell size (µm2) | Hexagonal cell ratio (%) | Coefficient of Variation (%) | Central corneal thickness (µm2) |
|---|---|---|---|---|---|---|---|---|
Jha | 2021 | 592 | DM | 2484.5 ± 299.5 | - | 39.9 ± 5.2 | 40.3 ± 6.1 | 522.1 ± 36.6 |
596 | Control | 2555.9 ± 258.2 | - | 44.6 ± 6.0 | 37.2 ± 6.1 | 514.9 ± 37.1 | ||
Chowdhury | 2021 | 131 | DM | 2762.08 ± 320.21 | - | 55.34 ± 5.82 | 31.60 ± 3.51 | 514.54 ± 38.17 |
131 | Control | 2771.46 ± 336.7 | - | 56.94 ± 7.00 | 30.85 ± 6.68 | 511.65 ± 32.64 | ||
Eichwalder | 2021 | 50 | DM | 2263 ± 352 | - | 57 ± 21 | 32 ± 9 | 532 ± 39 |
50 | Control | 2267 ± 292 | - | 55 ± 22 | 33 ± 9 | 515 ± 35 | ||
Tasli | 2020 | 195 | DM | 2427.94 ± 427.10 | 419.69 ± 71.98 | 66.94 ± 7.17 | 32.37 ± 6.16 | 539.01 ± 41.19 |
100 | Control | 2615.56 ± 106.80 | 374.74 ± 14.11 | 78.48 ± 6.56 | 30.29 ± 4.08 | 525.90 ± 28.79 | ||
Papadakou | 2020 | 72 | DM | 2297.9 ± 311.3 | 415.6 ± 61.3 | 46.3 ± 8.2 | - | 543.2 ± 38.7 |
88 | Control | 2518.3 ± 243.7 | 401.2 ± 43.2 | 48.8 ± 8.3 | - | 531.9 ± 37.2 | ||
Alagorie | 2020 | 120 | DM | 2295 ± 311 | 411.6 ± 52.1 | 49.1 ± 10.2 | 36.0 ± 6.2 | 544.2 ± 38.0 |
112 | Control | 2501 ± 302 | 408.2 ± 48.8 | 55.2 ± 10.0 | 34.9 ± 4.0 | 521.5 ± 31.5 | ||
Islam | 2017 | 149 | DM | 2494.47 ± 394.10 | 415.31 ± 95.34 | 52.42 ± 6.94 | 36.03 ± 4.26 | - |
149 | Control | 2574.46 ± 279.97 | 398.99 ± 50.78 | 52.83 ± 7.44 | 35.86 ± 4.39 | - | ||
El-Agamy | 2017 | 57 | DM | 2,491.98 ± 261.08 | - | 33.24 ± 10.25 | - | 545.61 ± 30.39 |
45 | Control | 2,629.68 ± 293.45 | - | 34.24 ± 8.73 | - | 539.42 ± 29.22 | ||
Storr-Paulsen | 2014 | 107 | DM | 2578 ± 77 | - | 58.0 ± 1.4 | 31.9 ± 1.0 | 546 ± 7 |
128 | Control | 2605 ± 66 | - | 58.5 ± 1.1 | 31.9 ± 0.9 | 538 ± 5 | ||
Choo | 2010 | 100 | DM | 2541.6 ± 516.4 | 397.6 ± 84.3 | 41.1 ± 19.6 | 67.2 ± 47.2 | 517.3 ± 53.4 |
100 | Control | 2660.1 ± 515.5 | 380.0 ± 80.4 | 45.2 ± 20.6 | 58.2 ± 43.0 | 510.8 ± 71.9 | ||
Keoleian | 1992 | 14 | DM | 2883 ± 280 | - | 68 ± 8 | - | - |
14 | Control | 3131 ± 483 | - | 74 ± 8 | - | - | ||
Shetlar | 1989 | 19 | DM | - | 426 ± 66 | - | - | - |
19 | Control | - | 395 ± 36 | - | - | - | ||
Schultz | 1984 | 14 | DM | 2472 ± 49.2 | 406.6 ± 7.7 | - | - | - |
10 | Control | 2625 ± 54 | 382.4 ± 7.9 | - | - | - | ||
Busted | 1981 | 34 | DM | 2686 ± 356 | - | - | - | - |
47 | Control | 2853 ± 386 | - | - | - | - |