Cardiovascular Diabetology – Endocrinology Reports

Table 2 Incretin effect and incretin hormone concentrations among 30 Tanzanian adults stratified by diabetes status

From: The incretin effect in type 2 diabetes in a Sub-Saharan African population

		Non diabetes control		T2D from HbA1c		T2D from OGTT
	Modality	Median	IQR	Median	IQR	Median	IQR	P
Incretin effect	OGTT/IVGI	0.50	0.41–0.64	0.61	0.26–0.74	0.47	0.24–0.52	0.45
GLP-1, tAUC	OGTT	1,055	712-1,599	1,085	880-1,118	1,082	972-1,711	0.87
GLP-1, tAUC	IVGI	435	313–535	357	326–384	686	413–942	0.07
GIP, tAUC	OGTT	37,996	26,567 − 40,586	36,668	33,888 − 46,386	41,502	26,393 − 53,141	0.79
GIP, tAUC	IVGI	8,137	7,166 − 21,213	4,580	3,473-7,512	12,804	8,307 − 14,079	0.06
Glucose, tAUC	OGTT	1,414	1,240-1,593	1,378	1,272-1,452	1,728	1,596-2,852
Glucose, tAUC	IVGI	1,466	1,324-1,537	1,421	1,329-1,466	1,743	1,630-3,062
Insulin, tAUC	OGTT	43,251	28,433 − 53,433	54,871	42,847 − 77,333	23,352	16,492 − 41,101
Insulin, tAUC	IVGI	16,486	15,332 − 30,167	23,537	19,441 − 39,660	11,041	8,631 − 25,331

Data are median, interquartile ranges (IQR) and p-values from Kruskal–Wallis one-way analysis of variance. Data on glucose and insulin during OGTT/IVGI is presented for informational purposes.
Abbreviations: T2D Type 2 diabetes, tAUC Total area under the curve, OGTT Oral glucose tolerance test, IVGI Intravenous glucose infusion

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ISSN: 3059-4057

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