Bone health in young adults with type 1 diabetes and progressive eGFR decline

Table 5 Relationship between radius HRpQCT parameters and demographic and diabetes variables

HRpQCT parameters	Hemoglobin A1C			Diabetes duration			BMI				Vitamin D level
HRpQCT parameters	R²	β	p	R²	β	p	R²	β		p	R²	β	p
Tt BMD (mgHA/cm³)	0.08	-1.2	0.8	0.09	1.3	0.6	0.1		0.2	0.8	0.09	-0.02	0.9
Tt. Ar (mm²)	0.1	3.0	0.5	0.2	-2.9	0.08	0.1		1.5	0.03	0.1	0.1	0.5
Ct BMD (mgHA/cm³)	0.1	-1.8	0.7	0.1	4.0	0.08	0.1		0.5	0.6	0.1	-0.1	0.5
Ct. Ar (mm²)	-0.03	0.5	0.7	-0.03	-0.3	0.6	-0.02		-0.1	0.6	-0.03	0.03	0.6
Ct.Th (mm)	0.07	-0.01	0.6	0.08	0.01	0.2	0.07		0.003	0.4	0.06	0.0001	0.9
Ct Pm (mm)	0.1	0.8	0.1	0.1	-0.2	0.4	0.1		0.1	0.1	0.1	0.02	0.5
Ct.Po (%)	-0.01	-0.6	1.0	-0.003	0.3	0.2	-0.01		-0.03	0.8	-0.02	-0.02	0.4
Ct.Po.Dm (mm)	-0.01	-1.5	0.3	-0.003	0.8	0.2	-0.01		-0.07	0.8	-0.02	-0.05	0.4
Tb BMD (mgHA/cm³)	0.4	2.6	0.4	0.4	-2.4	0.03	0.4		0.05	0.9	0.4	0.2	0.2
Tb.Ar (mm²)	0.02	-1.7	0.7	0.02	0.8	0.6	0.03		-1.3	0.05	0.02	0.1	0.4
Tb. N (1/mm)	0.1	4x10^-3	0.8	0.2	-0.02	0.01*	0.1		1x10^-5	1.0	0.2	1x10^-3	0.03
Tb. Sp (mm)	0.2	-0.003	0.7	0.2	0.01	0.004*	0.2		-5x10^-4	0.8	0.2	-8x10^-4	0.04
Tb. Th (mm)	0.4	0.002	0.3	0.4	1x10^-5	1.0	0.4		-8x10^-5	0.7	0.4	5x10^-5	0.4

vBMD volumetric bone mineral density, Ctcortical, Th thickness, Tb trabecular, Sp separation, N Number, Ct. Pm cortical perimeter, Ct. Po cortical porosity, Ct.Po.Dm cortical porosity diameter
Significance at p \(\le\)0.01. linear regression analysis with adjustment of covariates of relationship between HbA1C, diabetes duration, body mass index, 25 hydroxy-vitamin D level, and radius HRpQCT parameters. Adjusted R², beta coefficient and p values are reported

ISSN: 3059-4057