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Table 3 Relationship between bone biomarkers and eGFR decliner status

From: Bone health in young adults with type 1 diabetes and progressive eGFR decline

Variable

Whole cohort  mean (± SD)

eGFR decliner mean (± SD)

eGFR non decliner mean  (± SD)

Adjusted p value

Osteocalcin (pg/mL)

13448 (± 4882.1)

15443 (± 5461.8)

11889 (± 3737.3)

0.3

CTX (ng/mL)

0.57 (± 0.3)

0.65 (± 0.32)

0.51 (± 0.28)

0.2

P1NP (ng/mL)

78.3 (± 44)

93.95 (± 56.4)

65.9 (± 25.3)

0.7

Bs-ALP ( \({\varvec{u}}\)g/L)

20.6 (± 10)

23.9 (± 12.8)

17.9 (± 6.2)

0.5

  1. CTX c-terminal telopeptide, P1NP procollagen 1 intact n-terminal pro-peptide and Bs-ALP bone specific alkaline phosphatase
  2. Linear regression analysis with adjustment for covariates age, sex and 25 hydroxyvitamin D was performed