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Table 2 Autoantibody status combinations detected for each subject up to visit 2 (n = 57)

From: Heterogeneity of beta-cell function in subjects with multiple islet autoantibodies in the TEDDY family prevention study - TEFA

IAA (n positive subjects = 28)

GADA (n positive subjects = 52)

IA-2A (n positive subjects = 38)

ZnT8W/Q/R (n positive subjects = 40)

Autoantibody count

n (%) subjects with a given autoantibody combination

Autoantibody combination group

+

+

+

+

4

12 (21.1)

A

+

+

+

3

10 (17.5)

B

+

+

2

10 (17.5)

C

+

+

+

3

4 (7.0)

D

+

+

+

3

3 (5.3)

D

+

+

2

6 (10.5)

D

+

+

+

3

3 (5.3)

D

+

+

2

7 (12.3)

D

+

+

2

2 (3.5)

D

  1. The autoantibody combination group in the right-most column was defined based on the three most frequent autoantibody combinations, forming groups A-C (n = 12, 10, 10, respectively), with group D (n = 25) comprised of all remaining autoantibody combinations