Table 1 Laboratory evaluation of patients at the time of evaluation was notable for hypophosphatemia, low to low-normal 1,25-dihydroxyvitamin D level, and elevated fibroblast growth factor 23 (FGF23) level. Abnormal laboratory values are annotated with (H) if above the normal range and (L) if below the normal range
From: A rare cause of atraumatic fractures: case series of four patients with tumor-induced osteomalacia
Case 1 | Case 2 | Case 3 | Case 4 | |
|---|---|---|---|---|
Serum phosphorus (2.7–4.6 mg/dL) | 1.7 (L) | 1.0–1.5 (L) | 1.3–1.5 (L) | 2.1 (L) |
Serum creatinine (0.5–1.0 mg/dL) | 0.85 | 0.85 | 0.87 | 0.97 |
Serum calcium (8.6–10.3 mg/dL) | 10.0 | 9.4 | 9.9 | 9.0 |
Serum albumin (3.5–4.9 g/dL) | 4.6 | 4.5 | 4.3 | 4.0 |
Intact parathyroid hormone (10–65 pg/mL) | 25 | 61 | 113 (H) | 46 |
25-hydroxyvitamin D (25–100 ng/mL) | 52 | 18 (L) | 24 (L) | 27 |
1,25-dihydroxyvitamin D (18–78 pg/mL) | 18 | 7 (L) | 13 (L) | 20 |
Alkaline phosphatase (40–116 IU/L) | 145 (H) | 262–278 (H) | 246–326 (H) | 441 (H) |
Plasma FGF23 (< 180 RU/mL) | 264 (H) | 540 (H) | 2189 (H) | 548 (H) |